None listed
Conditions
Interventions
Symptomatic: Group A Type of group
Wheat germ 50 mg / k / d + tinidazole.
Group name:Asymptomatic: Group B Type of group
Placebo
Sponsors
INSTITUTO DE INVESTIGACION NUTRICIONAL,
Eligibility
Inclusion criteria
Inclusion criteria: • Giardia lamblia confirmed by ELISA. • Age greater than twelve months and less than or equal to 5 years (exceptionally older children). • Plan to reside in Lima for more than 2 months. • Symptomatic: Gastrointestinal symptom: diarrhea, abdominal pain, cramps. Abdominal distention, vomiting • Asymptomatic: No gastrointestinal symptoms
Exclusion criteria
Exclusion criteria: Symptomatic: • Dysentery (nalidixic acid will be indicated) • Severe diarrhea requiring hospitalization. • Significant medical condition (pneumonia, cancer, etc.) • Immuno suppressive therapy (eg steroids greater than or equal to 2mg / kg / d). • While you are taking an antibiotic for some reason. • Prior enrollment. • Wheat allergy. Asymptomatic: • Diarrhea. • Bloating or abdominal pain, vomiting. • Other gastrointestinal symptoms. • The other criteria of the symptomatic patient are repeated
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outcome name:Clinical evolution: based on the selection of data that will be evaluated according to the pre-established group, Stool test by ELISA test for giardia Measure:Frequency of parasitosis Timepoints:Durinf and after treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Outcome name:Stool test by ELISA test for giardia, microscope and coproculture according to the group. Blood test: hemoglobin. Measure:Laboratory Exams Timepoints:During and after treatment ; Outcome name:Age and education of parents, type of house (walls, floor) and basic services, number of people in the house, siblings. Measure:Sociodemographic information Timepoints:Before treatment ; Outcome name:Based on the selection of data that will be evaluated according to the pre-established group Measure:Clinical evolution Timepoints:During treatment | — |
Outcome results
None listed