Oral Health Anaesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: * Patients aged 18–50 years. * Healthy individuals classified as ASA I or II. * Mandibular first or second molars diagnosed with acute irreversible pulpitis. * Moderate to severe spontaneous pain. * Positive response to electric pulp testing. * Prolonged response to cold testing. * Absence of periapical radiolucency. * Closed root apices. * Ability to understand the visual analogue scale.
Exclusion criteria
Exclusion criteria: * Allergy to NSAIDs or enzyme preparations. * Pregnancy or lactation. * Use of analgesics or anti-inflammatory medications within 12 hours. * History of gastrointestinal ulceration. * Hepatic or renal disease. * Teeth with swelling or sinus tract. * Teeth exhibiting periodontal pockets greater than 4 mm. * Previously initiated endodontic treatment. * Non-restorable teeth. * Patients unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success of inferior alveolar nerve block anesthesia, defined as the ability to complete access cavity preparation and initial pulp extirpation with no or mild pain without the need for supplemental anesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| Electric pulp test EPT response; Pain intensity measured using the Visual Analog Scale (VAS) | — |
Countries
Egypt
Contacts
Associate professor faculty of oral and dental medicine Badr university at Cairo