Comparing intraocular pressure spikes following intravitreal anti-VEGF injection with and without paracentesis.

Comparative study of intraocular pressure spikes following intravitreal anti-vascular endothelial growth factor injections with and without paracentesis in patients attending eyeclinic, Lagos state university teaching hospital, Ikeja, Lagos.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202607821115847

Enrollment

Registered

2026-07-23

Start date

2026-06-19

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Interventions

Paracentesis

Without Paracentesis

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: • Patients who have been confirmed to have retinal diseases requiring Anti-VEGF (Irrespective of the number of times received) • Those who attend the Ophthalmology clinic of LASUTH • 18 years and above • Consent to participate in the study.

Exclusion criteria

Exclusion criteria: • Previous history of ocular surgeries (other than cataract surgery) • Aged <18 years • Corneal opacity occluding posterior segment examination • Had an intravitreal injection of corticosteroids in the last 6 months • Glaucoma patients • Prophylactic anti-glaucoma eyedrops during the perioperative period • Baseline IOP = 21 mmHg • Refusal to consent

Design outcomes

Primary

Measure	Time frame
Impact of Intravitreal Anti-VEGF on Intraocular pressure	—

Secondary

Measure	Time frame
Impact of Paracentesis on the Intraocular Pressure;Adverse effects of paracentesis	—

Countries

Nigeria

Contacts

Public ContactChidirim Esele

Resident Doctor

chidirime@gmail.com+2348161105827

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 10, 2026