Comparison between bilateral uterine artery ligation and temporary tourniquet application for controlling blood loss during surgical management of placenta previa major with suspected placenta accreta spectrum

A prospective randomized controlled trial comparing temporary tourniquet application versus bilateral uterine artery ligation for reducing intraoperative blood loss during surgical management of placenta previa major with suspected placenta accreta spectrum

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202607696756780

Enrollment

Registered

2026-07-14

Start date

2026-08-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Placenta previa major with suspected placenta accreta spectrum

Interventions

Temporary tourniquet application

Bilateral uterine artery ligation

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Pregnant women aged 18 years or older. Gestational age =34 weeks. Singleton pregnancy. Placenta previa major diagnosed by ultrasonography. Suspected placenta accreta spectrum based on ultrasound with or without MRI. Planned elective cesarean delivery. Ability and willingness to provide written informed consent

Exclusion criteria

Exclusion criteria: Emergency cesarean section due to uncontrolled hemorrhage. Confirmed placenta percreta with planned cesarean hysterectomy. Known coagulation or bleeding disorders. Multiple pregnancy. Major fetal congenital anomalies or intrauterine fetal demise. Severe maternal medical illness contraindicating study participation. Refusal to participate in the study.

Design outcomes

Primary

Measure	Time frame
Estimated intraoperative blood loss (mL)	—

Secondary

Measure	Time frame
Requirement for blood transfusion (number of packed red blood cell units transfused);Operative time (minutes);Postoperative hemoglobin change (g/dL);Need for cesarean hysterectomy;Maternal intraoperative and postoperative complications (bladder injury, ureteric injury, ICU admission, postoperative infection)	—

Countries

Egypt

Contacts

Public ContactHossam Rabie

Resident of Obstetrics and Gynecology Faculty of Medicine Minia University

hossamrabie22@gmail.com+201025241128

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 10, 2026