Corneal Parameter Changes After Corneal Collagen Cross-Linking in Patients with Keratoconus Using AS-OCT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202607620700858

Enrollment

Registered

2026-07-01

Start date

2025-02-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Interventions

Corneal Collagen Cross Linking

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age between 15 and 35 years both male and female patients diagnosed with progressive keratoconus Increase of =1.00 diopter (D) in the steepest keratometric (K) reading Increase of =1.00 D in manifest cylinder Increase of =0.50 D in manifest refraction spherical equivalent Decrease in corneal thickness >30 µm and Keratoconus stages I–III according to Amsler–Krumeich classification with a clear cornea

Exclusion criteria

Exclusion criteria: History of ocular trauma Previous intraocular surgery Corneal thickness less than 400 µm History of herpetic ocular infection Post-LASIK ectasia and presence of other corneal ectatic disorders

Design outcomes

Primary

Measure	Time frame
Changes in corneal parameters measured by AS-OCT after corneal collagen cross-linking (CXL) in keratoconus patients.	—

Secondary

Measure	Time frame
Keratometry changes (Kmax) Corneal topography indices Complications after CXL Disease progression arrest rate	—

Countries

Egypt

Contacts

Public ContactAhmed Samir

MSc researcher

ahmadsmsm007@gmail.com+201115119836

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026