Post major gynaecogical surgery pain management
Conditions
Interventions
PENTAZOCINE DICLOFENAC
NEFOPAM DICLOFENAC
Sponsors
Bankole ADEWUMI
Merit Healthcare Ltd
Biocodex
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: This will include women scheduled for major gynaecology surgery who are • 18 years of age or above • Scheduled for elective major gynaecological surgery. • American Society of Anesthesiologists (ASA) Physical Status I–III. • Able to understand and communicate using the DVPRS • Patients with normal renal and liver function test
Exclusion criteria
Exclusion criteria: This will include participants scheduled for major gynaecology surgery who are • With history of prolonged use of opioid analgesics e.g. sickle cell patients, patients with neuropathy etc • Diagnosed or being managed for cancers or malignancies • Known allergy or hypersensitivity to nefopam, pentazocine or diclofenac. • With deranged liver or kidney function test or coagulopathy • History of seizure disorder of severe psychiatric illness • Currently pregnant. • Visually impaired
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The average postoperative pain score during the first 24 hours following surgery measured using the Defense and Veterans Pain Rating Scale (DVPRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of adverse drug reaction observed for either of the study group;The effects of either of the study drugs on the patients’ haemodynamical parameter inclusive of Blood pressure, Pulse Rate, Respiratory Rate and Oxygen saturation;The requirement for rescue analgesia in either group - time to first rescue analgesia and number of times rescue analgesia given;The overall level of satisfaction of the post-operative pain management | — |
Countries
Nigeria
Contacts
Public ContactBankole ADEWUMI
Senior Resident Doctor at Department of Obstetrics and Gynaecology University College Hospital
Outcome results
None listed