Skin and Connective Tissue Diseases
Conditions
Interventions
Intralesional steroids
Microneedling with methotrexate
Sponsors
Al Azhar university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Co-operative patient who is willing and able to comply with the treatment protocol and follow-up visits. Participants must have stable vitiligo, meaning that the extent and severity of their vitiligo have not significantly changed in the past 6 months
Exclusion criteria
Exclusion criteria: Patients with keloidal tendency. Patients receiving topical or systemic treatment for vitiligo and phototherapy during the previous 6 months. Patients with active lesions. Participants with a history of hypersensitivity to methotrexate or any of its excipients. Participants with a history of liver disease or liver function abnormalities. Participants with a history of bleeding disorders or receiving anticoagulant therapy. Participants who are pregnant or breastfeeding. Participants with active skin infections or skin conditions that would contraindicate the use of microneedling or intralesional injections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the degree of repigmentation | — |
Secondary
| Measure | Time frame |
|---|---|
| complications of the procedure | — |
Countries
Egypt
Contacts
Public ContactMofreh Ismail
Assistant professor of Dermatology Venereology and Andrology Faculty of Medicine AlAzhar University
Outcome results
None listed