Efficacy of Locally Delivered Black Seed Oil Gel (Nigella Sativa) as an Adjunctive To Non-Surgical Treatment in Stage II Grade B Periodontitis Patients: A Randomized Controlled Clinical Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202607535790876

Enrollment

Registered

2026-07-22

Start date

2025-03-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

placebo gel

Nigella sativa gel

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Ages from 30 : 55 years Medically free patient Probing pocket depth (PPD) = 5 Clinical attachment loss 3-4 mm. Optimal compliance as evidenced by no missing appointments and positive attitude towards oral hygiene.

Exclusion criteria

Exclusion criteria: Current smoker patients. 2Patients with traumatic occlusion unless receiving adequate treatment. Gingival recession Patients consuming antibiotics in the last three months. Patients with any other periodontal treatment for at least 6 months ago. 6. Pregnant and lactating females

Design outcomes

Primary

Measure	Time frame
Microbiological Assessment : Quantitative polymerase chain reaction (qPCR) used to count the number of porphyromonas gingivalis	—

Secondary

Measure	Time frame
probing pocket depth;clinical attachment loss;bleeding on probing;gingival index	—

Countries

Egypt

Contacts

Public ContactDoaa Ahmed Yousef

Assistant Professor

doaa.bayoumi@dent.tanta.edu.eg01006882900

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026