Cold saline irrigation vs room temperature saline irrigation in RIRS.

Cold Saline Irrigation in Retrograde Intrarenal Surgery: A Prospective Randomized Comparative Study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202607520333163

Enrollment

260

Registered

2026-07-09

Start date

2025-09-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urological and Genital Diseases Kidney Disease

Interventions

Retrograde intrarenal surgery using saline at room temperature irrigation

Retrograde intrarenal surgery using cold saline irrigation.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age: from 20 to 60 years · Sex: male and female. Pelvicalyceal single stone 2 to 3 cm

Exclusion criteria

Exclusion criteria: Patients with solitary kidney or bilateral urolithiasis. Active UTI Patients with distal ureteric obstruction . Renal stones on Anomalous kidney Uncompansated Coagulopathy.

Design outcomes

Primary

Measure	Time frame
Decreasing the intrarenal temperature to prevent postoperative urinary tract infection after RIRS;The clarity of the endoscopic surgical field according to visualization scale	—

Secondary

Measure	Time frame
Stone free rate via post operative Pelviabdomenal Ultrasound and CT;Renal thermal injury evaluated by Biochemical markers ( Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule-1 ) secreted by parenchymal cells via blood sample Preoperative and postoperative	—

Countries

Egypt

Contacts

Public ContactMahmoud Abdelhamid;Mahmoud Abdelhamid Elshamy;Elshamy

Urology Resistant;Urology Resistant

dr.mahmoud.elshamy.5797@gmail.com;dr.mahmoud.elshamy.5797@gmail.com+201028495275;+201028495275

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026