lung protective mechanical ventilation in ARDS

Mechanical Power as an Independent Predictor of 28-Day Mortality in Adult Patients with ARDS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202606917558736

Enrollment

200

Registered

2026-06-09

Start date

2026-06-21

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory

Interventions

Mechanical Power

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Age = 18 years • Diagnosis of ARDS according to Berlin definition • PaO2/FiO2 = 300 mmHg with PEEP = 5 cmH2O • Invasive mechanical ventilation in pressure controlled mode • Enrollment within 24 hours of ARDS diagnosis ARDS diagnosis will be confirmed independently by two ICU physicians based on clinical and radiological criteria.

Exclusion criteria

Exclusion criteria: • Pregnancy • Chronic home mechanical ventilation • DNR/DNI status at enrollment • Enrollment in interventional ventilator trials • ECMO initiation within the first 72 hours Early deaths and patients ventilated<3 days will NOT be excluded to avoid survivorship bias.

Design outcomes

Primary

Measure	Time frame
28-day all-cause mortality	—

Secondary

Measure	Time frame
ICU mortality;Hospital mortality ;Duration of mechanical ventilation (among survivors) ;ICU length of stay (among survivors) ;Hospital length of stay (among survivors) ;Ventilator-free days at day 28 count of days alive and free from invasive ventilation between day 0 and day 28)	—

Countries

Egypt

Contacts

Public Contactkhaled gaballah

assistant professor of anesthesia and intensive care medicine

khgaballah@gmail.com00201016009073

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026