Effects of Aerobic Exercise on Inflammatory Biomarkers, Pain, and Quality of Life in Patients with Non-Specific Chronic Low Back Pain

Effects of Aerobic Exercise Programme on Tumor Necrosis Factor-Alpha, Interleukin-6, C-Reactive Protein, Pain Intensity, and Quality of Life Among Patients with Non-Specific Chronic Low Back Pain in Nigeria: A Controlled Clinical Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202606887164888

Enrollment

Registered

2026-06-18

Start date

2025-11-20

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases

Interventions

Aerobic Exercise Programme

Usual Care

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: i. Participants whose ages ranged between 18 and older. ii. Participants who have had a history of Mechanical NON-SPECIFIC CHRONIC LOW BACK PAIN at least for 6 months. iii. Participants who never had a history of spinal decompression surgery.

Exclusion criteria

Exclusion criteria: i. Those with history of spinal surgeries ii. Those with a complain of mechanical low back pain less than 6 months. iii. presence of cognitive impairment Mini-Mental State Examination (MMSE) score (less than 18 or < 24 in patients) iv. Pregnant women

Design outcomes

Primary

Measure	Time frame
Pain Intensity;Tumor Necrosis Factor-Alpha (TNF-a);Interleukin-6 (IL-6);C-Reactive Protein (CRP)	—

Secondary

Measure	Time frame
Quality of Life (QoL)	—

Countries

Nigeria

Contacts

Public ContactAdaeze Onyekwelu

University of Nigeria Enugu Campus

onyekweluadaeze9@gmail.com+2349030843598

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026