Laser Treatment of Gingival Hyperpigmentation Using Four Different Wavelengths

Comparative Evaluation of Melanin Gingival Depigmentation Using Four Different Laser Wavelengths: A Split-Mouth Comparative Clinical Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202606836433454

Enrollment

Registered

2026-06-01

Start date

2024-07-23

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Laser assisted gingival depigmentation

Comparative laser treatment group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Adult individuals with physiological gingival pigmentation in the maxillary and the mandibular anterior esthetic zone. • Score 2 of melanin pigmentation index (MPI)

Exclusion criteria

Exclusion criteria: 1. Gingival pigmentation that may be caused by systemic diseases or medications taken. 2. Periodontal disease. 3. Previous mucogingival surgery at the treated region. 4. Caries or infection in anterior teeth. 5. Smokers. 6. Pregnant or lactating women

Design outcomes

Primary

Measure	Time frame
Clinical effectiveness of gingival depigmentation using four different laser wavelengths.	—

Secondary

Measure	Time frame
All laser wavelengths (groups) were fast, comfortable and effective with comparable results showing significant improvement in pigmentation indices throughout the follow-up period.	—

Countries

Egypt

Contacts

Public ContactHana Elkateb

Postgraduate Researcher Faculty of Dentistry Alexandria University

hanamelkateb@hotmail.com+201004847771

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026