Surgery Anaesthesia
Conditions
Interventions
dexmedetomidine in modified thoracolumbar interfascial plane block
morphine in modified thoracolumbar interfascial plane block
Sponsors
Mansoura University hospitals
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Patient's aged 18 – 50 of either sex. • Patients scheduled for lumbar spine fusion surgery. • American Society of Anesthesiologists (ASA) I, II. • Ability to understand and provide informed consent.
Exclusion criteria
Exclusion criteria: • Patient refusal. • Coagulation disorders or current use of anticoagulant therapy. • Skin lesions or infection at site of needle insertion. • Known allergy to local anesthetics, dexmedetomidine or morphine, • History of chronic pain, opioid dependence or psychiatric illness. • American Society of Anesthesiologists (ASA) III, IV. • Body mass index (BMI) >35 kg/ m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -Time to first postoperative analgesic request and total opioid consumption in first 24 postoperative hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1- Intraoperative additional analgesic (fentanyl) needs. 2- Pain scores (VAS) at rest and movement in the first 24 postoperative hours. 3- Intraoperative hemodynamics (Non-invasive blood pressure (NIBP), Heart rate and oxygen saturation). 4- Block related complications (Hypotension, nausea and vomiting). 5- Patient satisfaction. | — |
Countries
Egypt
Contacts
Public ContactOla Taha Abd Eldayem
Professor of anesthesia
Outcome results
None listed