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The Effect of Upper Cervical Spine Manipulation Compared to a Control and No Intervention on Heart Rate Variability in Male Endurance Athletes

The Effect of Upper Cervical Spine Manipulation Compared to a Control and No Intervention on Heart Rate Variability in Male Endurance Athletes

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202606639763213
Enrollment
60
Registered
2026-06-22
Start date
2026-06-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuroscience, Physiology Cardiology

Interventions

Sponsors

Durban University of Technology Faculty of Health Science
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Male sex between the ages of 18 and 40 years A homogenous male sample is preferred to exclude interfering factors of a female sample such as hormones and reproductive cycles. Ages 18-40 is preferred to reduce the risk of exclusion considering the age incidence of diseases. Normal blood pressure (more than 90/50 mmHg and less than 140/90 mmHg based on vitals of endurance athletes). No alcohol, tobacco, caffeine or other stimulants 24 hours before the consult. Runner that runs more than 32 km per week.

Exclusion criteria

Exclusion criteria: History of cervical spine trauma or surgery. History of heart disease (coronary artery disease, arrhythmia, cardiomyopathy), vascular disease (artery stenosis, varicose veins, embolism), diabetes mellitus, hypertension, cancer, stroke or chronic inflammatory disease (rheumatoid arthritis, psoriatic arthritis). Abnormalities upon cardiovascular and physical examination (the physiological changes of the heart, particularly in athletes will be accommodated for). Any abnormalities detected such as murmurs, thrills, arrhythmia, abnormal vital signs and any other physical findings that are a cause for concern relating to overall health will result in the participant being excluded from the study. Other more rare contra-indications to chiropractic cervical spine manipulation that may be revealed during the consultation (Hutting et al., 2018).

Design outcomes

Primary

MeasureTime frame
Heart rate variability / HRV;Root mean square of successive differences between normal heart beats / RMSSD

Secondary

MeasureTime frame
High frequency bands / HFs;Low frequency bands / LFs;LF/HF Ratio;Heart Rate ;Percentage of successive normal sinus RR intervals greater than 50ms / pNN50

Countries

South Africa

Contacts

Public ContactJunaid Shaik

CoSupervisor PhD

junaids@dut.ac.za+27837790358

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 10, 2026