Respiratory
Conditions
Interventions
standard care
Sponsors
faculty of applied health science technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Adult patients (= 18 years old). • Who have received invasive mechanical ventilation for more than 72 hours. • Who are clinically stable and deemed ready to undergo a Spontaneous Breathing Trial (SBT) and weaning attempt, according to the unit's protocol. • Written informed consent obtained from the patient or their legal authorized representative.
Exclusion criteria
Exclusion criteria: • Previous tracheostomy before the weaning attempt. • Severe neuromuscular disease affecting respiration (e.g., ALS, myasthenia gravis). • Death before extubation or within 48 hours post-extubation without reintubation. • Refusal or inability to provide consent. . Patients who received prophylactic NIV or HFNC immediately after extubation (i.e., planned immediate support).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to determine and compare the predictive accuracy of IWI and CORE index for reintubation within 48 hours of extubation (extubation failure) | — |
Secondary
| Measure | Time frame |
|---|---|
| • To explore the relationship between index values and ICU outcomes such as length of mechanical ventilation, ICU stay, hospital stay, and time to reintubation. • To record the use of postextubation support with non-invasive ventilation (NIV) or high-flow nasal cannula (HFNC) and its association with index values. | — |
Countries
Egypt
Contacts
Public Contactkhaled gaballah
assistant professor of anesthesia and intensive care
Outcome results
None listed