Comparative Efficacy of Pericapsular Nerve Group (PENG), Lumbar Erector Spinae Plane (LESP), and Their Combination for Postoperative Analgesia After Total Hip Arthroplasty

Comparative Efficacy of Pericapsular Nerve Group (PENG), Lumbar Erector Spinae Plane (LESP), and Their Combination for Postoperative Analgesia After Total Hip Arthroplasty: A Prospective, Randomized, Controlled, Double-Dummy Trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202606470377992

Enrollment

132

Registered

2026-06-09

Start date

2026-05-28

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

PENG block

LESP block

The Combined PENG and LESP blocks group

Sham block

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA I–III, elective primary THA under spinal anesthesia

Exclusion criteria

Exclusion criteria: If the patient refuses participation, has chronic pain or opioid use, contraindications to regional anesthesia (such as infection at the injection site, coagulopathy, or allergy to local anesthetics), neurological deficits, cognitive impairment, inability to consent or report pain, revision/bilateral THA, or BMI <18.5 or =40 kg/m²

Design outcomes

Primary

Measure	Time frame
Area under the curve (AUC) of postoperative pain scores (Static VAS) over the first 24 hours	—

Secondary

Measure	Time frame
Cumulative opioid consumption at 24 and 48 hours;Time to first rescue analgesia ;Static and dynamic VAS scores;Early functional recovery;Patient satisfaction;Block-related complications and adverse events	—

Countries

Egypt

Contacts

Public ContactKhalid Gaballah

Assistant Professor of Anesthesiology

khgaballah@gmail.com+201016009073

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026