Primary Postpartum Haemorrhage
Conditions
Sponsors
seif
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Pregnant women aged 20 – 40 years, with parity (1–4), carrying a live singleton fetus at term (gestational age =37 weeks but <42 weeks), scheduled for primary emergency caesarean section under spinal anaesthesia at Asokoro District Hospital, Abuja, who provide written informed consent.
Exclusion criteria
Exclusion criteria: Women with multiple gestations, known coagulopathies or bleeding disorders, severe pre-eclampsia/eclampsia, placenta previa or accreta, history of thromboembolic events, known allergy to tranexamic acid, significant hepatic, cardiac or renal impairment, those undergoing general anaesthesia, or those who decline to give informed consent will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure will be the mean intraoperative blood loss (in millilitres) between the two groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome measures will include: The incidence of excessive blood loss, ( defined as estimated blood loss of =1000 mL intraoperatively); The mean change in haematocrit levels; The need for additional uterotonic agents or blood transfusion; and the occurrence of maternal adverse drug events, including nausea, vomiting, hypotension, and thromboembolic complications. | — |
Countries
Nigeria
Contacts
Public ContactKWARI SHIKTIRA DANLADI
Consultant Obstetrician and Gynaecologist
Outcome results
None listed