Pregnancy and Childbirth
Conditions
Sponsors
Ani Frank Onyeka
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women with singleton pregnancies at 37 to 40 weeks gestational age scheduled for elective caesarean section. Para 1 to 4. Women who provide written informed consent. Women aged 20–40 years.
Exclusion criteria
Exclusion criteria: Women with known bleeding disorders or coagulation abnormalities, A history of thromboembolic disease, Severe medical conditions such as hepatic or renal impairment, liver pathology, hypertensive disorders in pregnancy, antepartum haemorrhage. Known hypersensitivity to oxytocin or tranexamic acid, or those undergoing emergency caesarean section, Women who do not consent will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measure will be the mean intraoperative blood loss (mL) between the two groups | — |
Secondary
| Measure | Time frame |
|---|---|
| secondary outcomes will include the incidence of excessive blood loss (defined as blood loss =1000 mL intraoperatively). the mean change in haematocrit levels, need for additional uterotonic agents or blood transfusion, and maternal drug adverse events such as nausea, vomiting, hypotension, thromboembolic events. | — |
Countries
Nigeria
Contacts
Public ContactCHIKA JOYCE EZEUGO
Chief Consultant Obstetrician and Gynaecologist
Outcome results
None listed