Prophylactic tranexamic acid for reducing intraoperative blood loss during caesarean section in women at high risk of postpartum haemorrhage: A double-blind placebo controlled randomised study

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202605853075255

Enrollment

204

Registered

2026-05-21

Start date

2026-04-13

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum haemorrhage

Interventions

Tranexamic acid

Sterile water for injection

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: High risk women undergoing caesarean section, specifically those with previous PPH uterine fibroids, multiple pregnancy, placenta praevia, polyhydraminos

Exclusion criteria

Exclusion criteria: Coagulopathy Uterine rupture

Design outcomes

Primary

Measure	Time frame
The mean intraoperative blood loss and change in hematocrit levels 48 hours postoperatively	—

Secondary

Measure	Time frame
The use of additional uterotonic agents, need for blood transfusion or surgical intervention, incidence of postpartum maternal anaemia and the occurrence of adverse effects.	—

Countries

Nigeria

Contacts

Public ContactIkechukwu Kennedy Ajaegbu

Medical doctor

ikechukwuajaegbu60@gmail.com08038439071

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Jun 29, 2026