Efficacy of Mifepristone for Cervical Ripening and Induction of Labour at University of Benin Teaching Hospital: A Randomised Controlled Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202605702730487

Enrollment

Registered

2026-05-18

Start date

2026-06-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

placebo

Mifepristone

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Patients with uncomplicated and low risk pregnancy planned for induction of labour at term 2. Unfavourable cervix with a reactive non-stress test

Exclusion criteria

Exclusion criteria: 1. Patients who required immediate/urgent delivery within 72 hours 2. Patients with previous Caesarean section or myomectomy 3. Grand multiparous women (Para 5 and above) 4. Multiple gestation 5. Patients with known allergy to mifepristone or prostaglandin 6. Patients with suspected intrauterine growth restricted foetus 7. Patients with gestational diabetes mellitus/diabetes in pregnancy or Cushing syndrome

Design outcomes

Primary

Measure	Time frame
Mean Bishops score changes, participants with favourable cervix and participants who transform to spontaneous active phase of labour	—

Secondary

Measure	Time frame
induction-to-delivery time interval, vaginal delivery rate, Caesarean section rate, safety profile assessing hyperstimulation, primary postpartum haemorrhage, feotal heart irregularity, low APGAR score and admission to SCBU	—

Countries

Nigeria

Contacts

Public ContactCharles Efe Ogwah

Senior registrar. Nigerian Medical Association

ogwahcharles@gmail.com2348062551649

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026