Effect of propofol versus sevoflurane on the optic nerve sheath diameter in patients undergoing laparoscopic sleeve gastrectomy

Comparison of the Effect of propofol versus sevoflurane on the optic nerve sheath diameter in patients undergoing laparoscopic sleeve gastrectomy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202605680434286

Enrollment

Registered

2026-05-08

Start date

2025-10-05

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

propofol

sevoflurane

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 80 patients ASA class II and III with age ranged from 20- 40 years with BMI 35-40 kg/m2 or higher scheduled for laparoscopic sleeve gastrectomy

Exclusion criteria

Exclusion criteria: • Previous history of neurological diseases. • Cerebrovascular diseases or diabetes. • Previous brain surgery. • Ophthalmological diseases, glaucoma. • Patients whose CO2 pneumoperitoneum will be interrupted.

Design outcomes

Primary

Measure	Time frame
Measurement of the mean optic nerve sheath diameter (ONSD) at different time intervals in propofol (TIVA) and sevoflurane groups.	—

Secondary

Measure	Time frame
• Heart rate (beats/min). • Non-Invasive mean arterial blood pressure (mmHg). ;Recovery time from anaesthesia:	—

Countries

Egypt

Contacts

Public ContactAhmed hashem

professor of ophthalmology

Ahmedosama722@hotmail.com01003828881

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026