Non-operative versus operative management of uncomplicated acute appendicitis: a randomized controlled study in Sierra Leone

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202605655002550

Enrollment

Registered

2026-05-19

Start date

2020-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery

Interventions

Non inferiority randomised controlled

open appendectomy in management of uncomplicated acute appendicitis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who were diagnosed with uncomplicated acute appendicitis at the emergency department, outpatient clinic, and surgical outpatients' clinic of the Connaught Hospital. Patients aged 18 years and above, who presented within 48 hours with clinical features of uncomplicated acute appendicitis Abdominal ultrasound scan confirming uncomplicated acute appendicitis Patients with an Alvarado Score of 6 and above.

Exclusion criteria

Exclusion criteria: Non-consenting patients, Immunocompromised patients, Patients with clinical or radiological features of complicated appendicitis, e.g., generalised peritonitis, appendiceal abscess, or perforated appendicitis Patients managed non-operatively with antibiotics at an outside facility, Pregnant women Patients allergic to medications in the study protocol

Design outcomes

Primary

Measure	Time frame
absence of symptoms of acute appendicitis after non operative management	—

Secondary

Measure	Time frame
Quality of life, ;length of hospital Stay;cost of care	—

Countries

Sierra Leone

Contacts

Public ContactAiah Lebbie

Head of Department

aiahlebbie2005@gmail.com+23276787537

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026