Paediatrics
Conditions
Interventions
lactulose plus probiotic
lactulose group
Sponsors
armed forces collage of medicine
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Children were included in the study if they fulfilled all of the following criteria: • Age between 4 and 15 years • Both males and females • Diagnosis of functional constipation according to Rome IV criteria • Regular follow-up at the gastroenterology outpatient clinic • Written informed consent obtained from parents or legal guardians
Exclusion criteria
Exclusion criteria: Children were excluded from the study if they had any of the following: • History suggest Organic causes of constipation, including: o Hirschsprung disease o Cystic fibrosis o Neurological disorders o Spinal anomalies o Anatomical anorectal malformations o Metabolic diseases such as hypothyroidism o Irritable bowel syndrome o Intellectual disability o Previous gastrointestinal surgery • Current use of medications affecting gastrointestinal motility • Immunocompromised states • Known hypersensitivity to probiotic components
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Successful treatment, defined as improvement of signs and symptoms according to Rome IV diagnostic criteria for functional constipation. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Tolerance and palatability • Occurrence of adverse effects | — |
Countries
Egypt
Contacts
Public Contactmohamed elemam
assistant lecturer of pediatrics
Outcome results
None listed