Assessing Fluid Responsiveness Using Optic Nerve Sheath Diameter versus Inferior Vena Cava Collapsibility in Critically Ill Patients

Evaluation of Optic Nerve Sheath Diameter vs IVC Collapsibility as a Biomarker for Assessing Fluid Resuscitation Status in Critically Ill Patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202605504308095

Enrollment

Registered

2026-05-08

Start date

2025-01-21

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluid responsiveness in a critically ill patient

Interventions

Fluid Bolus

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age between 30-70 ASA IV patients Requiring fluid resuscitation due to septic shock, hemorrhagic shock, or other causes of acute circulatory failure

Exclusion criteria

Exclusion criteria: • A history of ocular surgery or pre existing ophthalmic disease or intracranial pathology • previous upper midline abdominal surgery • Any condition or state that may hinder ultrasonographic examination • Mechanically ventilated patients

Design outcomes

Primary

Measure	Time frame
The primary outcome was the correlation between IVC derived fluid responsiveness and concurrent changes in ONSD, with the aim of determining whether ONSD may serve as a reliable alternative assessment tool.	—

Secondary

Measure	Time frame
ONSD changes upon fluid administration;IVC collapsibility index changes upon fluid administration	—

Countries

Egypt

Contacts

Public ContactMai ElSayed

Lecturer of Anesthesia and Surgical ICU

m_mohamed165@alexmed.edu.eg00201287459922

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Jun 29, 2026