HIV/AIDS
Conditions
Interventions
TA Technique
Standard TA Technique
Sponsors
National Cancer Institute
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Study population Inclusion criteria 1. 25-49 years old 2. Living with HIV Inclusion criteria specific to the feasibility study 1. Intact cervix 2. Willing to return to facility at 6 months 3. Willing and able to provide informed consent 4. Positive hrHPV or VIA test within 3 months of enrollment
Exclusion criteria
Exclusion criteria: Exclusion criteria specific to the feasibility study 1. Screened for cervical cancer in last 6 months 2. Currently pregnant or less than 6 weeks postpartum 3. Prior diagnosis of cervical cancer 4. A history of treatment for cervical precancer 5. Total hysterectomy 6. Currently receiving treatment for any cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To evaluate the feasibility, acceptability, and safety of implementing a two-probe TA technique among WLWH at the CASCADE Network CS9 site and collaborating health facilities. 2. To augment ongoing quality control efforts of clinical procedures in the screening-to-treatment cascade that support the implementation of future clinical trials for cervical cancer prevention. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Difference in the proportion of women with hrHPV persistence. • Difference in the proportion of women requiring further treatment • Comparative patient-reported acceptability scores • Comparative frequency and severity of adverse events | — |
Countries
South Africa
Contacts
Public ContactNqobile;Bongekile Myeni;Zuma
CAPRISA;CAPRISA
Outcome results
None listed