HIV/AIDS
Conditions
Interventions
Enhanced Standard of Care
SUSTAIN DSD
Sponsors
University of Cape Town
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Adults (=18 years or age), • Living with HIV, • On a dolutegravir-based first-line ART regimen, • Evidence of a care gap (>28 days late for appointment) or having a raised viral load (>50 copies/ml) in the preceding year, either from SUSTAIN study data or from clinic records, • Able to provide full informed consent, • Willingness to comply with study procedures, including providing regular update of contact details or locator information.
Exclusion criteria
Exclusion criteria: • Clinical conditions as assessed by the ART clinicians as requiring clinic-based follow-up e.g. tuberculosis or epilepsy, • Sustained retention in care (no gaps of >28days) and viral suppression in the preceding year, • Plans to leave Cape Town permanently within the next 24 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be viral suppression (VL <50 c/ml) at 24 months post-enrollment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will include viral suppression at 12 months, retention in care at study clinics (and in care at any other clinic) at 12 and 24 months (measured by the proportion attending club or clinic visits at months 12 and 24), treatment interruptions (measured using pharmacy refill data), ART adherence (measured using urine tenofovir rapid assays and medication possession ratio calculated from pharmacy refill data), and success in HIV self-management of care at 12 and 24 months. | — |
Countries
South Africa
Contacts
Public ContactDapheline Moralie
Project Manager
Outcome results
None listed