Circulatory System Cardiology Anaesthesia
Conditions
Interventions
A placebo
ondansetron
Sponsors
Mansoura University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients of both sexes aged 18 to 45 undergoing unilateral lower abdominal surgeries using spinal anesthesia. 2. Height from 160 cm to 180 cm. 3. American Society of Anesthesiologist physical status I, II . 4. Body mass index less than 30 kg/m².
Exclusion criteria
Exclusion criteria: 1. Patients who refuse to participate in the study 2. Elevated BP (>160/100 mm Hg) 3. Failed spinal anesthesia 4. Patients with known cardiovascular disease 5. Patients with known cerebrovascular disease 6. Patients with known neurological, neurodegenerative or psychiatric disease 7. Patients with known liver cell failure 8. Clinical history of diabetes. 9. Contraindication to spinal anesthesia e.g., coagulopathy. 10. Patients with known allergy to ondansetron.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be the incidence of hypotensive episodes within I hour from the start of spinal anesthesia. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes will be the number of hypotensive episodes, post spinal bradycardia episodes and MAP and HR measured at 5, 10, 15, 20, 30, 45, and 60 min after spinal anesthesia, | — |
Countries
Egypt
Contacts
Public ContactNabil Abdelraouf
Department of Anesthesia and Surgical Intensive Care Faculty of Medicine Mansoura University Mansoura Egypt Phone
Outcome results
None listed