Anaesthesia
Conditions
Interventions
Standard care
Sponsors
Aya Mohamed
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients were eligible for inclusion if they were aged between 20 and 60 years old and classified as ASA physical status I or II. Patients had to be classified as morbidly obese with a BMI greater than 40 kg/m². A confirmed clinical diagnosis of obstructive sleep apnea was mandatory based on documented clinical symptoms.
Exclusion criteria
Exclusion criteria: Patients were excluded if they had a known allergy or hypersensitivity to ibuprofen or other NSAIDs. Other reasons for exclusion were an estimated operative time exceeding 4 hours, a history of congestive heart failure, uncontrolled diabetes mellitus, a history of chronic pain or chronic opioid consumption (defined as use for more than one week in the past three months). Patients with hepatic or renal impairment, known bleeding diathesis, a history of intracranial hemorrhage, or active gastrointestinal tract problems (such as gastritis or gastric bleeding) were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The intensity of postoperative pain, assessed using the VAS at the PACU and subsequently at 2, 6, 12, and 24 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes included analgesic efficacy and safety. Efficacy was measured by the time to first rescue analgesia, defined as the time interval (in minutes) from the end of surgery until the patient first requested the rescue dose of nalbuphine. Patient satisfaction was also assessed using a 5-point Likert scale, where 5=excellent and 1=no pass. | — |
Countries
Egypt
Contacts
Public ContactAhmed Soliman
Mansoura University
Outcome results
None listed