Comparison of effectiveness of isometric and isotonic quadriceps strengthening exercises on pain intensity, joint stiffness and physical function in patients with knee osteoarthritis

Comparison of the effectiveness of isometric and isotonic quadriceps strengthening exercises on pain intensity, joint stiffness and physical function in individuals with knee osteoarthritis: a quasi-experimental trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202603911904768

Enrollment

Registered

2026-03-31

Start date

2024-03-06

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases

Interventions

Isometric quadriceps strengthening exercise

Isotonic quadriceps strengthening exercise

No Control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (i) diagnosis of primary knee osteoarthritis based on the American College of Rheumatology clinical criteria19; (ii) ability to ambulate independently with or without an assistive device.

Exclusion criteria

Exclusion criteria: (i) a history of knee surgery; (ii) non-ambulatory status; (iii) presence of underlying inflammatory pathologies (e.g., rheumatoid arthritis); (iv) severe cardiopulmonary conditions contradicting exercise; and (v) cognitive impairment preventing comprehension of instructions.

Design outcomes

Primary

Measure	Time frame
Outcomes included pain intensity (Visual Analog Scale)	—

Secondary

Measure	Time frame
Joint stiffness and physical function (Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC])	—

Countries

Nigeria

Contacts

Public ContactOlawale Oshomoji

Research Assistant

waleeoshomoji@student.oauife.edu.ng+2349049208430

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026