Pregnancy and Childbirth Fertility-female
Conditions
Interventions
medroxyprogesterone acetate
Sponsors
Ogonnaya Chinasa Obire
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: )EGG DONOR: 1)Women aged between 21 and 27 years. 2)Normal hormonal screening. 3) BMI 21 to 25kg/m2 4) Serology Negative 5)No previous ovarian surgery. 6)No ovarian cysts. 7)Adequate ovarian reserve as determined by serum FSH level on day 3 of the menstrual cycle of <12mlU/ml. 8)Written informed consent obtained. B)RECIPIENT: 1)Women aged =35 years, except those with premature ovarian failure (After 35, the risk of aneuploidy, diminished ovarian reserve, and poor oocyte quality rises significantly, making them the group most likely to benefit from donor oocytes). 2)Patients with premature ovarian failure at any age. 2)Infertility diagnosis with normal uterine cavity. 3)Written informed consent obtained.
Exclusion criteria
Exclusion criteria: 1. Known chromosomal abnormalities in either partners or the egg donor. 2. Previous ovarian surgery or radiotherapy. 3. Known autoimmune or endocrine disorders. 4. Severe medical or psychiatric conditions that would preclude IVF treatment. 5. Unable to give informed consent or comply with study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure was the number of oocytes retrieved. | — |
Secondary
| Measure | Time frame |
|---|---|
| . Secondary outcomes included the duration of ovarian stimulation in days, the incidence of cycle cancellation, the fertilisation rate, the clinical pregnancy rate, and Ovarian hyperstimulation syndrome (OHSS). | — |
Countries
Nigeria
Contacts
Public ContactEkweani John
Supervisor
Outcome results
None listed