high-risk pregnant women including placenta praevia, placental abruptio, and uterine rupture
Conditions
Interventions
Tranexamic acid
water for injection
Sponsors
Ezugwu Ifeanyi Anthony
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients who have given consent for caesarean delivery. The pregnant women must be at least 18 years old. The participant must be a high-risk pregnancy. Term pregnancies (37 weeks to 41 weeks + 6days).
Exclusion criteria
Exclusion criteria: Patient who refused to give consent Uterine rupture Intra-uterine fetal death History of bleeding disorders Known allergy to tranexamic acid History of thrombo-embolism Low risk pregnancies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measures will be the mean intra-operative blood loss during caesarean delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures will include use of additional uterotonics, need for blood transfusion, need for surgical intervention, postpartum maternal anaemia and adverse effects (nausea, vomiting, thrombo-embolism and coagulopathy, seizures, headaches, back ache, anaphylactic reaction and impaired vision), perinatal outcomes such as first and fifth minute appearance, pulse, grimace, activity and respiratory movement (APGAR SCORES) and neonatal intensive care unit admission. | — |
Countries
Nigeria
Contacts
Public ContactIjeoma Ezeome
Head of Department of Obstetrics and Gynaecology University of Nigeria Teaching Hospital
Outcome results
None listed