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Effect of preoperative submucosal dexamethasone injection on postoperative complications following mandibular third molar surgery.

Effect of preoperative submucosal dexamethasone injection on postoperative complications following mandibular third molar surgery. A prospective, randomized, double blind clinical trial at the Korle Bu Teaching Hospital

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202603708240509
Enrollment
56
Registered
2026-03-24
Start date
2026-03-02
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Sponsors

Dickson Afram
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Generally healthy patients (American Society of Anesthesiologists-ASA class I status) with no previous history of third molar surgery 2. Patients with radiographically diagnosed impacted mandibular third molars within the ages of 18 and 50 years. 3. Patient with impacted mandibular third molar with Pederson pre-operative difficulty assessment score of 7 or less 4. Patient who consents for the study.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of systemic diseases including diabetes, hypertension, asthma, stomach ulcer, etc. 2. Patients with a history of allergy or adverse reaction to corticosteroids. 3. Patients taking any anti-inflammatory, antibiotic, or analgesic medications within 2 weeks prior to surgery. 4. Patients with active infection or inflammation at the surgical site. 5. Pregnant women and lactating mothers

Design outcomes

Primary

MeasureTime frame
Submucosal dexamethasone injection would offer adequate anti-inflammatory effect on the postoperative complications after mandibular third molar surgery

Secondary

MeasureTime frame
Other post-operative complications including dry socket, surgical site infection, haemorrhage

Countries

Ghana

Contacts

Public ContactDennis Appiah Bolfrey

Specialist Korle Bu Teaching Hospital

dabolfrey@yahoo.com+233247112360

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Jun 29, 2026