A Novel Gelatin/ß-Tricalcium Phosphate Sponge with Concentrated Growth Factors as an Alternative to Autogenous Bone in Intrabony Defect Treatment: A Clinical Trial

Gelatin Beta-Tricalcium-Phosphate Sponge with Concentrated Growth Factors in the Treatment of Intrabony Defects

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202602908285015

Enrollment

Registered

2026-02-19

Start date

2024-12-25

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

gelatin sponge loada with betatricalcium phosphate with concentrated growth factor

autogenous bone

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Each patient should have at least two intrabony defects with pocket depth>5mm 2. intrabony defect > 3mm deep detected by panoramic x ray and CBCT 3. Optimal complience as evidenced by no missed treatment appointment and positive attitude towards oral hygiene 4.No evidence of gingival recession

Exclusion criteria

Exclusion criteria: 1. Pregnant 2. Uncontrolled diabetes , 3. Patient on radiotherapy or chemotherapy 4. Patient with bleeding disorder that can affect wound healing 5. Smoking 6.Immunodificiency disorder

Design outcomes

Primary

Measure	Time frame
Clinical periodontal parameters were assessed at baseline (pre-surgery) and at 6 months post-surgery using a calibrated periodontal probe guided by a custom-made occlusal stent to ensure measurement reproducibility. The recorded parameters included bleeding on probing (BOP), probing pocket depth (PPD), and clinical attachment level (CAL),	—

Secondary

Measure	Time frame
Radiographic Assessment (CBCT): were obtained for each patient at baseline and 6 months post-surgery using standardized parameters (constant voltage, current, exposure time, and field of view). A single trained technician performed all scans. The following were measured from coronal, sagittal, and 3D reconstructed sections ,Bone Density (BD): Assessed in Hounsfield Units (HU) within the defect region. Defect Volume (DV): Calculated in cubic millimeters (mm³) using the scanner's dedicated software. Duplicate measurements were made for all parameters, and the mean value was used for analysis	—

Measure

Time frame

Radiographic Assessment (CBCT): were obtained for each patient at baseline and 6 months post-surgery using standardized parameters (constant voltage, current, exposure time, and field of view). A single trained technician performed all scans. The following were measured from coronal, sagittal, and 3D reconstructed sections ,Bone Density (BD): Assessed in Hounsfield Units (HU) within the defect region. Defect Volume (DV): Calculated in cubic millimeters (mm³) using the scanner's dedicated software. Duplicate measurements were made for all parameters, and the mean value was used for analysis

—

Countries

Egypt

Contacts

Public ContactAhmed dawood

researcher

PG_167568@dent.tanta.edu.eg+201008874800

Outcome results