Oral Health
Conditions
Interventions
Injectable platlet rich fibrin
Hyaluronic Acid
Sponsors
safinaz sleh mohamed saeed
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adults aged 18–45 years Systemically healthy (ASA I–II) and medically fit for periodontal procedures. Presence of thin gingival biotype at the selected site (gingival thickness <1.5 mm). Natural tooth/teeth present at the study site (no implant at the target site). Site located in the esthetic zone/premolar area Plaque control acceptable (e.g., Plaque Index =20% or as per protocol). Gingival inflammation controlled (e.g., Bleeding on probing within acceptable limits). No active periodontal disease requiring immediate treatment at the target site (stable periodontal condition). Willingness to comply with study visits and procedures (4 sessions + 6-month follow-up). Signed written informed consent
Exclusion criteria
Exclusion criteria: Current smokers or tobacco users (including shisha/vaping) or >10 cigarettes/day (choose your cutoff). Pregnancy or lactation. Untreated caries, defective restoration, or cervical lesion at the target site affecting measurements. Orthodontic treatment affecting the target site during the study period. Allergy/hypersensitivity to hyaluronic acid product components (for HA group safety). Participation in another clinical trial within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in gingival thickness (GT)(measured by transgingival probing, and supported/confirmed by CBCT and digital intraoral scanning (DIS)) | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in keratinized tissue width (KTW) clinical measurement ;Patient-centered outcomes : pain/discomfort using VAS and patient questionnaire | — |
Countries
Egypt
Contacts
Public Contactahmed mohamed elghayesh
lecturer
Outcome results
None listed