Surgery
Conditions
Interventions
traditional thyroidectomy
thyroidectomy with intraoperative utilization of methylene blue spray
thyroidectomy with intraoperative use of carbon nanoparticles
Sponsors
Al Azhar university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients between 18 and 60 years old penign thyroid disease and failed medical management with the indication for thyroidectomy
Exclusion criteria
Exclusion criteria: patients above 60 years old patients with hypocalcemia or hypoparathyroidism renal impairment major cardiac diseases G6PD deficiency pregnant patients patients unfit for general surgery patients with methylene blue allergies patients having received monoamine oxidase (MAO) inhibitors like isocarboxazid, tranylcypromine, and phenelzine (because methylene blue is a potent inhibitor of MAO and, in combination with serotonergic agents, can produce serotonin toxicity in the perioperative period).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of parathyroid glands identified and preserved through surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| levels of serum PTH and calcium at postoperative | — |
Countries
Egypt
Contacts
Public ContactAbdelmonem Abdelfattah Mohammed
Assistant professor of surgery Faculty of medicine Al Azhar University Assuit branch Egypt
Outcome results
None listed