analgesic effect of pregabalin Vs memantine for mastectomy

Preemptive analgesic effect of pregabalin versus memantine for postmastectomy pain: a randomized clinical trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202602625664031

Enrollment

Registered

2026-02-16

Start date

2026-02-10

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Interventions

pregabalin

memantine

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: patients aged 20–60 years American Society of Anesthesiologists (ASA I-II) patients scheduled for elective modified radical mastectomy under general anesthesia.

Exclusion criteria

Exclusion criteria: Patients known to be hypersensitive or contraindication to the studied drugs impaired renal & liver functions history of chronic pain and on medications for this uncontrolled medical disease (cardiovascular, pulmonary, endocrine, neurological, psychiatric, diabetes)

Design outcomes

Primary

Measure	Time frame
Severity of acute postoperative pain	—

Secondary

Measure	Time frame
chronic pain ;neuropathic pain ;quality of life;quality of sleep;Total dose of intraoperative and postoperative rescue analgesic ;adverse effects	—

Countries

Egypt

Contacts

Public ContactMona Elghamry

Assistant professor anesthesiology department faculty of medicine Tanta university

drmonagh19802000@gmail.com+201221413987

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026