(Predictive Performance of the Integrative Weaning Index and CORE Index for Reintubation Following Mechanical Ventilation Weaning)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202602548270786

Enrollment

214

Registered

2026-02-03

Start date

2026-02-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory

Interventions

CORE IWI index assessment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Adult patients (= 19 years old). • Who have received invasive mechanical ventilation for more than 72 hours. • Who are clinically stable and deemed ready to undergo a Spontaneous Breathing Trial (SBT) and weaning attempt, according to the unit's protocol. • Written informed consent obtained from the patient or their legal authorized representative.

Exclusion criteria

Exclusion criteria: • Previous tracheostomy before the weaning attempt. • Severe neuromuscular disease affecting respiration (e.g., ALS, myasthenia gravis). • Death before extubation or within 48 hours post-extubation without reintubation. • Refusal or inability to provide consent.

Design outcomes

Primary

Measure	Time frame
The primary outcome of this study is to determine and compare the predictive accuracy of IWI and CORE index for reintubation within 48 hours of extubation (extubation failure)	—

Secondary

Measure	Time frame
ICU Outcomes MV duration and length of stay;post extubation respiratory support;time to reintubation	—

Countries

Egypt

Contacts

Public Contactkhalid Gaballah

assistant prof anesthesiology of intensive care and pain management

khaled.gaballah@gmail.com+201016009073

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026