Cancer
Conditions
Interventions
Injection of ICG at cervix of endometrial cancer patient to detect sentinel lymph node
Sponsors
Oncology Center Mansoura University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1- Patients (=18 years of age) with FIGO stage IB and more grade II endometrioid EC and high-grade EC (grade 3 endometrioid, serous, carcinosarcoma, clear cell, undifferentiated or dedifferentiated, and mixed high grade) scheduled for laparoscopic primary hysterectomy with an intent to complete full staging. 2- Written informed consent. 3- Clinically node negative patients with no gross extra-uterine extension or peritoneal metastasis.
Exclusion criteria
Exclusion criteria: 1- Grade I and FIGO stage 1A grade II endometrioid EC. 2- Recurrent, or suspected advanced EC (extra-uterine extension or clinically positive lymph nodes). 3- Prior retroperitoneal surgery or abdominopelvic radiotherapy. 4- Need for Neoadjuvant therapy. 5- Plans to omit lymphadenectomy based on surgical or anesthetic risk. 6- Pregnancy. 7- Iodide allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of overall and bilateral detection rate of SLNB using ICG, so this will help to determine whether SLN biopsy, using ICG, could, in the future, replace systemic lymphadenectomy for surgical staging of intermediate and high-grade endometrial cancer. this outcome will be measured post operative after paraffin result | — |
Secondary
| Measure | Time frame |
|---|---|
| Determine whether SLN biopsy, using ICG, could, in the future, replace systemic lymphadenectomy for surgical staging of intermediate and high grade endometrial cancer. | — |
Countries
Egypt
Contacts
Public ContactKhaled Gaballa
Associate professor of surgical oncology Oncology Center Mansoura University
Outcome results
None listed