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Contribution of Haematological Parameters to the Outcome Prediction of Severe Asthma Exacerbation

Contribution of Haematological Parameters to the Outcome Prediction of Severe Asthma Exacerbation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202601821561911
Enrollment
200
Registered
2026-01-14
Start date
2023-05-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haematological Disorders Respiratory

Interventions

neutrophil to lymphocyte ratio monitoring

Sponsors

Reasearch Unit for Respiratory Failure and Mechanical Ventilation UR 22SP01
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: -Age between 16 and 65 years -Patient consenting to participate in the study (written consent) and to undergo a CBC (complete blood count). -In the event of an emergency department visit or admission to the ICU or pulmonology: patient presenting with a first episode of wheezing dyspnea, with a history strongly suggestive of asthma, and with later confirmation of the disease in pulmonology through pulmonary function testing (the patient will be recontacted after their pulmonology consultation if the initial management of the exacerbation took place in the emergency department, in order to obtain their pulmonary function test results). -In the event of an emergency department visit or ICU admission: patient already followed in pulmonology for chronic obstructive pulmonary disease, with a history strongly suggestive of asthma.

Exclusion criteria

Exclusion criteria: -For patients already followed in pulmonology who presented to the emergency department or were admitted to the intensive care unit: the diagnosis of asthma was ruled out after reviewing the patient’s medical records (the primary care physician will be contacted to obtain data from prior investigations). -For patients presenting with an inaugural episode of wheezing dyspnea in the emergency department or admitted to the intensive care unit: after consultation in pulmonology, the diagnosis of asthma was ruled out (the patient will be recontacted after their pulmonology consultation to obtain their pulmonary function tests). -Patients who withdraw consent at any point during the study.

Design outcomes

Primary

MeasureTime frame
To assess the association between NLR and the initial severity of an asthma exacerbation.

Secondary

MeasureTime frame
To assess the association between NLR and the course of an asthma exacerbation until discharge.

Countries

Tunisia

Contacts

Public ContactJalila Ben Khelil

Dr

jalila.benkhelil@fmt.utm.tn0021698327390

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026