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Comparing the monotherapy VS combination therapy in the management of overactive bladder

Assessing the Effect of Using Solifenacin, Mirabegron or Their Combination in Treatment of Overactive Bladder: A Comparative Study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202601758391175
Enrollment
150
Registered
2026-01-13
Start date
2024-08-12
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urological and Genital Diseases

Interventions

Solifenacin 5mg tab
Mirabegron 50 mg tab
Solifenacin 5mg tab and Mirabegron 50 mg tab

Sponsors

Minia Urology and Nephrology University Hoipital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: age ranging between 19-65 years. Both sex. Patients who have primary overactive bladder (Patients or their first guardians accepted to participate in the current study and accepted to provide informed written consent) .

Exclusion criteria

Exclusion criteria: - Patients who did not give consent. - Patients 65yrs. - Patients with the presence of liver disease, chronic kidney disease, closed-angle glaucoma, stress incontinence, or neurological cause of abnormal detrusor activity. - Patients in which drugs could not be given (hypersensitivity to drugs, any history of bladder retention, closed-angle glaucoma). - Patients who had a history of any operation related to voiding dysfunction (TAP, Prolapse and BPH). - Patients who failed medical treatment for overactive bladder - elderly male patients complaining from BPH and overactive bladder at the same settings.

Design outcomes

Primary

MeasureTime frame
Compare the efficacy of Solifenacin 5mg ,Mirabegron 50mg or their Combination in the management of overactive bladder in short term follow up 3months duration

Secondary

MeasureTime frame
compare the side effects and safety of Solifenacin 5mg ,Mirabegron 50mg or their Combination in the management of overactive bladder in short term follow up 3months duration

Countries

Egypt

Contacts

Public ContactAli Mohamed

Assistant Lecturer of urology faculty of medicine minia university

aliabdelwahab890@gmail.com00201121851167

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026