Haematological Disorders
Conditions
Interventions
laboratory assesment of CD19 and CD38 in healthy controls
laboratory assesment of CD19 and CD38in ITP patients
Sponsors
sohag unuversity hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -pt with idiopathic immune thrombocytopenia
Exclusion criteria
Exclusion criteria: -seconary causes of immune throbocytopenia and malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Outcome: “Difference in CD19 and CD38 expression levels on peripheral blood lymphocytes between patients with idiopathic immune thrombocytopenia and healthy controls at baseline, measured by flow cytometry (% positive cells and mean fluorescence intensity) , | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Correlation between CD19 and CD38 expression levels and platelet count in ITP patients. 2. Comparison of CD19 and CD38 expression between newly diagnosed and chronic ITP patients. 3. Assessment of changes in CD19 and CD38 expression after first-line therapy (optional follow-up at 3 months). | — |
Countries
Egypt
Contacts
Public Contactsheren filip Aziz
prof. of clinical pathology
Outcome results
None listed