Evaluation of Ozonated Olive Oil–Chitosan Nanoparticles as an Adjunctive Therapy to Non-Surgical Periodontal Treatment: A Randomized Controlled Clinical Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202601553696389

Enrollment

Registered

2026-01-13

Start date

2024-10-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Nanogel

SRP alone

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Suprabony pockets with probing pocket depths = 6 mm and CAL = 5 mm. - Medically free Patients. - Patients capable of maintaining proper oral hygiene and attending follow-up appointments. - Single-rooted teeth.

Exclusion criteria

Exclusion criteria: - Any complicated bone loss patterns, such as vertical bone defects. - Pregnant and lactating. - Smoker patients. - Patients with traumatic occlusion, unless they have received appropriate treatment. - Presence of gingival recession. - Patients who have taken antibiotics, anti-inflammatories, anticonvulsants, or immunosuppressive medications in the past three months - Patients who have had any other periodontal procedures within the last six months.

Design outcomes

Primary

Measure	Time frame
Plaque Index (PI)	—

Secondary

Measure	Time frame
Superoxide dismutase (SOD) levels in gingival crevicular fluid	—

Countries

Egypt

Contacts

Public ContactElsayedamr Basma

Patient Information Manager

elsayedamr@yahoo.com00201223106023

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026