Can Probiotics Improve Metabolic Health and Well-Being in Type 2 Diabetes?

Probiotic Intervention (S.Boulardii) and Its Effects on Metabolic Parameters and Psychological Health in Type 2 Diabetes Mellitus: A Randomized Controlled Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202601489244572

Enrollment

Registered

2026-01-27

Start date

2025-12-06

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine

Interventions

probiotic

control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients diagnosed with type 2 diabetes aged 40 to 65 years. Their treatment had to be stable for at least 3 months consent.

Exclusion criteria

Exclusion criteria: Type 1 Diabetics or any other type of diabetes, Pregnant or breastfeeding women, Patients with progressive neoplasia or ongoing cancer treatment. Patients who have received antibiotic or probiotic treatment in the last 3 months patients with chronic inflammatory or autoimmune diseases

Design outcomes

Primary

Measure	Time frame
to evaluate the effect of probiotic supplementation on the metabolic balance glycemia fasting HbA1c and lipidic profile	—

Secondary

Measure	Time frame
to evaluate the effect of probiotic supplementation on mental health of patients with type 2 diabetes.	—

Countries

Tunisia

Contacts

Public Contactrym ben othman

university of tunis el manar

rym.benothman@fmt.utm.tn+2169990402

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026