The Impact of Varicocelectomy on improving Sperm DNA Fragmentation and abnormal Semen Parameters in subfertile men with clinical varicocele (prospective randomized controlled study)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202512856668704

Enrollment

100

Registered

2025-12-10

Start date

2025-09-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-male

Interventions

Varicocelectomy

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Male patients less than 44 years old Subfertile men Clinical varicocele Abnormal semen parameters per WHO 2021 Elevated sperm DNA fragmentation index (DFI > 15%)

Exclusion criteria

Exclusion criteria: Previous scrotal surgery Hormonal abnormalities Immunocompromised patients Severe oligozospermia

Design outcomes

Primary

Measure	Time frame
change in semen parameters after varicocelectomy	—

Secondary

Measure	Time frame
change in sperm DNA fragmentation index after varicocelectomy	—

Countries

Egypt

Contacts

Public ContactWael Gamal

Professor of Urology sohag university

saadwael738gma1@gmail.com+201002808738

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026