A comparative study of intraocular pressure control using selective laser trabeculoplasty and latanoprost as initial treatments for primary open angle glaucoma and ocular hypertension in Lagos State University Teaching Hospital.

Selective laser trabeculoplasty versus latanoprost as first line treatments for primary open angle glaucoma and ocular hypertension: A comparative analysis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202512840605479

Enrollment

138

Registered

2025-12-24

Start date

2025-12-15

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Interventions

Selective laser trabeculoplasty

Latanoprost eye drops

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 years and over 2. Patients newly diagnosed as Primary open angle glaucoma or ocular hypertension 3. Patients with elevated intraocular pressure greater than 21mmHg( an average of 3 readings taken on 3 different clinic visits) 4. Patients categorized as early or moderate primary open angle glaucoma ( cup to disc ratio 0.5 to 0.7, visual field analysis MD-6dB to -12 dB) 5. Patients who agree to participate

Exclusion criteria

Exclusion criteria: 1. A prior medical, surgical or laser treatment for glaucoma 2. Patients diagnosed as primary congenital glaucoma 3. Advanced glaucoma ( cup to disc ratio 0.8 or greater, visual field analysis MD more than -12dB 4. Patients with media opacities such as cloudy cornea, cataract vitreous haemorrhage 5. Patients with history of ocular trauma or uveitis 6. Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
Percentage intraocular pressure reduction from baseline. Assessment of treatment side effects. Secondary out come will be health related and vision related quality of life of patients.	—

Secondary

Measure	Time frame
Health and vision related quality of life	—

Countries

Nigeria

Contacts

Public ContactChidinma Nwokedi

Public enquiries

bisinwokedi@gmail.com07060645714

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026