Nervous System Diseases Surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Both sexes, aged >12 or <70 with a pituitary macroadenoma, pneumatized sphenoid sinus treated who underwent endonasal transsphenoidal resection under endoscopic endonasal approach.
Exclusion criteria
Exclusion criteria: Exclusion criteria were age 70 years, non-pneumatized sphenoid sinus, recurrent pituitary adenoma, pituitary microadenoma and sinus infection (Sinusitis). All cases had preoperative evaluation including full history taking including [Demographic Information including (Age, sex, race, ethnicity, occupation, and medical history), presenting symptoms including (Visual disturbances, endocrinological symptoms including (Symptoms related to hormone hypersecretion, symptoms related to hormone deficiency including (Headache, neurological symptoms, history of previous pituitary surgery or radiotherapy), duration and progression of symptoms, past medical and surgical history, medication history, especially hormone therapies, family history of pituitary or endocrine disorders and review of systems including other endocrine functions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor resection degree. Classified based on Juraschka et al. [1] as partial resection (< 70%), subtotal resection (70–90%), near-total resection (90–100%), and gross-total resection (100%). | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complications, such as diabetes insipidus (DI), cranial nerve palsy, internal carotid artery damage, CSF leak, CSF leak necessitating a lumbar drain, headache, epistaxis, sinusitis, visual complications, deep venous thrombosis, pulmonary embolism, vasospasm, subdural hygroma, hematoma, seizure, hydrocephalus, meningitis, coma, and death were all observed | — |
Countries
Egypt
Contacts
Kafrelsheikh University