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Endoscopic Management of Pituitary Adenoma: Endonasal Approach

Endoscopic Management of Pituitary Adenoma: Endonasal Approach

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
PACTR
Registry ID
PACTR202512728520659
Enrollment
25
Registered
2025-12-03
Start date
2024-06-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases Surgery

Interventions

Endoscopic endonasal transsphenoidal resection

Sponsors

Ahmed Soliman
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Both sexes, aged >12 or <70 with a pituitary macroadenoma, pneumatized sphenoid sinus treated who underwent endonasal transsphenoidal resection under endoscopic endonasal approach.

Exclusion criteria

Exclusion criteria: Exclusion criteria were age 70 years, non-pneumatized sphenoid sinus, recurrent pituitary adenoma, pituitary microadenoma and sinus infection (Sinusitis). All cases had preoperative evaluation including full history taking including [Demographic Information including (Age, sex, race, ethnicity, occupation, and medical history), presenting symptoms including (Visual disturbances, endocrinological symptoms including (Symptoms related to hormone hypersecretion, symptoms related to hormone deficiency including (Headache, neurological symptoms, history of previous pituitary surgery or radiotherapy), duration and progression of symptoms, past medical and surgical history, medication history, especially hormone therapies, family history of pituitary or endocrine disorders and review of systems including other endocrine functions.

Design outcomes

Primary

MeasureTime frame
Tumor resection degree. Classified based on Juraschka et al. [1] as partial resection (< 70%), subtotal resection (70–90%), near-total resection (90–100%), and gross-total resection (100%).

Secondary

MeasureTime frame
Postoperative complications, such as diabetes insipidus (DI), cranial nerve palsy, internal carotid artery damage, CSF leak, CSF leak necessitating a lumbar drain, headache, epistaxis, sinusitis, visual complications, deep venous thrombosis, pulmonary embolism, vasospasm, subdural hygroma, hematoma, seizure, hydrocephalus, meningitis, coma, and death were all observed

Countries

Egypt

Contacts

Public ContactMohamed Moustafa

Kafrelsheikh University

mohamedmoustafa451996@gmail.com00201091012731

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026