Single intravenous bolus versus continuous infusion of tranexamic acid to reduce blood loss in abdominal myomectomy: a randomized controlled trial in Lagos, Nigeria

SINGLE INTRAVENOUS BOLUS VERSUS CONTINUOUS INFUSION OF TRANEXAMIC ACID TO REDUCE BLOOD LOSS IN ABDOMINAL MYOMECTOMY: A RANDOMIZED CONTROLLED TRIAL IN LAGOS, NIGERIA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202512619740287

Enrollment

102

Registered

2025-12-10

Start date

2025-03-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine Fibroids

Interventions

TXA Continuous Infusion

Tranexamic Acid Bolua

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: i. Women aged 18–50 years old. ii. Women with symptomatic fibroids scheduled for myomectomy

Exclusion criteria

Exclusion criteria: i. History of hypersensitivity to the studied drug. ii. Preoperative anaemia (Hb < 10g/dl) iii. Pretreatment with GnRHa, Depo Provera or OCPs iv. Previous abdominal surgery v. Cervical or low corporeal lateral wall fibroid.14 vi. Chronic Liver Disease vii. Patients with known bleeding disorders viii. Past thromboembolic disorders

Design outcomes

Primary

Measure	Time frame
Intra-operative blood loss	—

Secondary

Measure	Time frame
Need for blood transfusion, Duration of the surgery and Duration of Hosptal stay	—

Countries

Nigeria

Contacts

Public ContactOluwakemi WIndapo

Senior Registrar Federal Medical Centre Ebute Metta

bolawindapo@gmail.com+2348023099282

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026