DRAIN-FURS Trial: Drainage-Assisted Flexible Ureteroscopy versus Ureteral Access Sheath FURS for Upper Urinary Tract Stones

A Prospective Randomized Controlled Trial Comparing Drainage-Assisted Flexible Ureteroscopy Using Percutaneous Nephrostomy Versus Ureteral Access Sheath in the Management of Upper Urinary Tract Stones

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202512556567081

Enrollment

140

Registered

2025-12-24

Start date

2026-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urological and Genital Diseases

Interventions

Drainage Assisted Flexible Ureteroscopy

Standard Flexible Ureteroscopy with Ureteral Access Sheath

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age =18 years Renal and/or upper third ureteric stones =20 mm Eligible for flexible ureteroscopy Ability to provide informed consent

Exclusion criteria

Exclusion criteria: 1. Staghorn or multiple calyceal stones. 2. Abnormal renal anatomy (horseshoe, duplex, malrotated kidney, PUJ obstruction, diverticulum). 3. Concomitant ureteric stones or ureteral pathology. 4. Active urinary tract infection or untreated bacteriuria. 5. Bleeding diathesis or anticoagulant use not correctable. 6. Pregnancy. 7. Severe comorbidities precluding anesthesia. 8. Previous renal surgery on the same side. 9. Solitary kidney, CKD patients or inability to complete follow-up.

Design outcomes

Primary

Measure	Time frame
Overall perioperative complications (assessed using Clavien–Dindo grade)	—

Secondary

Measure	Time frame
• Operative time (minutes). • Fluoroscopy time (seconds) and radiation dose (mGy·cm² if available). • Post-op stenting (yes/no; dwell time). • Length of stay (days). • Retreatment/auxiliary procedures within 3 months.	—

Countries

Egypt

Contacts

Public ContactAbdalla Homouda

Lecturer and consultant of Urology

abdallah.hamouda@med.tanta.edu.eg00201123911654

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026