Studying the effects of Norepinephrine, Phenylephrine and Ephedrine Boluses on Neonatal Blood Gases During Caesarean Section Under Spinal Anesthesia: A Comparative Prospective Randomized Study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202511922251165

Enrollment

120

Registered

2025-11-05

Start date

2025-11-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Anaesthesia

Interventions

Phenylephrine

Norepinephrine

Ephidrine

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: physical status II according to ASA classification

Exclusion criteria

Exclusion criteria: - Patients with physical status other than II according to ASA classification. - Pervious caesarean section. - Contraindications to spinal anesthesia (coagulopathy, site infection, severe Aortic stenosis, Increasing ICT, Allergy). - Pre-eclampsia and Eclampsia. - Ischemic heart diseases. - Severe anemia (Hemoglobin is less than 10 g/dl). - Impaired liver or renal function. - Allergy to any of the drug included in this study.

Design outcomes

Primary

Measure	Time frame
Umbilical cord arterial blood gas values (immediately after delivery)	—

Secondary

Measure	Time frame
Neonatal Apgar scores. (at 1 and 5 min). Incidence of hypotension (SBP < 80% baseline). Incidence of nausea or vomiting.	—

Countries

Egypt

Contacts

Public ContactMohammed Mahrous

lecturer

abdoezz335@gmail.com0201091328413

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026