Circulatory System Nutritional, Metabolic, Endocrine
Conditions
Interventions
Blood sampling for thyroid and adrenal hormones in patients with septic shock
Sponsors
Radwa mahmoud
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1-patients who match the diagnostic criteria for sepsis/septic shock as stated in the Sepsis and Septic Shock 3.0 guidelines published in 2016. 2- who are over 18 years old and admittedto the critical care unit (ICU) from with infections that have been visually or culture-identified . 3-patients are eligible for inclusion (Rhodes et al., 2017) after a consent from the patients or first degree relatives .
Exclusion criteria
Exclusion criteria: 1- Patients refuse to be enrolled in the study. 2- Patients with previous endocrinal disorders. 3- Patients receiving corticosteroid or thyroid hormonal therapy . 4- Pregnancy or lactation. 5- Previous endocrinal gland surgery . 6- Individuals with pacing rhythms, bundle branch blocks (QRS interval >120 ms), multiple premature ventricular complexes, bundle branch blocks (QRS interval >120ms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cortisol and thyroid hormones pattern in relation to death versus discharge. | — |
Secondary
| Measure | Time frame |
|---|---|
| -ICU Mortality: Patients were kept under observation until they passed away or were discharged. -New ECG alterations: keeping an eye out for extended QT intervals, ischemia alterations, or new arrhythmias. -The length of the intensive care unit Stay: The length of time spent there was noted. -Duration of mechanical ventilation: Monitoring the duration of mechanical ventilation. -The length of time spent on vasopressor therapy was recorded. -Continuous Renal Replacement Therapy (CRRT) Use. | — |
Countries
Egypt
Contacts
Public ContactMohamed Faisal
Prof of endocrinology
Outcome results
None listed